dr hab. Sławomir Makowiec | Gdańsk University of Technology

The degradation of dicamba as a persistent herbicide was studied with the combined application of UV and formic acid (FA) as a novel advanced reduction process (ARP). The effects of key parameters of FA concentration, dissolved organic matter, and inorganic anions were studied. A 97 % degradation and 94 % dechlorination of dicamba were obtained through the combination of UV and FA (UV-FA) at a dicamba concentration of 0.023 mM...

A new method for the preparation of tetrahydroquinolin-2-one derivatives is presented. This approach involves a two-step reaction between enaminones and acylating agents, immediately followed by electrophilic cyclization, all within a single synthesis procedure, eliminating the need to isolate intermediates. The entire process is facilitated by the use of acyl Meldrum’s acids which not only shortens the preparation time of the...

Herein, we report the synthesis of new compounds with demonstrated anticancer properties based on the 2,3,4,9- tetrahydro-1H-carbazole scaffold. The Fischer indolization method was used to close the heterocyclic motif. The synthesis method’s scope and limitations were thoroughly assessed through a series of experiments. Biological assays revealed that two thioamide compounds exhibited significant anticancer activity against MCF-7,...

Presence of pharmaceuticals, especially antibiotics, in industrial and domestic effluents causes serious damage to the environment. Classic wastewater treatment processes, in particular conventional biological treatment methods, are not sufficient to rapidly eliminate antibiotics. Typically, Advanced Oxidation Processes (AOPs) based on activation of hydrogen peroxide, ozone or persulfate for formation of particular type of radical...