NCh - Biochemistry
1. Synthesis and evaluation of novel anticancer compounds and construction of organic carrier–drug conjugates
Among acridine derivatives with anticancer activity five main classes of compounds: nitroacridines, 9-anilinoacridines, pyrazoloacridines, imidazoacridines, and triazoloacridines, can be distinguished. Compounds from different classes differ both in mechanism of action and spectrum of anticancer activity. The examination of anticancer compounds metabolism and mechanism of their activity has to be examined.