The antifungal activity of 5‐hydroxy‐4‐oxo‐L‐norvaline (HONV), exhibited under conditions mimicking
human serum, may be improved upon incorporation of this amino acid into a dipeptide
structure. Several HONV‐containing dipeptides inhibited growth of human pathogenic yeasts
of the Candida genus in the RPMI‐1640 medium, with minimal inhibitory concentration values
in the 32 to 64 μg mL−1 range. This activity was not affected by multidrug...